The Northern Ireland Executive has agreed that theatres and concert venues can reopen from 18:00 on Tuesday.
Ministers met earlier after delaying the decision, saying they wanted more information about risks.
There have been other modest changes to Covid-19 restrictions, including an increase in the number of people who can meet indoors.
Fully vaccinated people returning to Northern Ireland from so-called amber countries will not have to quarantine.
As part of the move to allow theatres and concert venues to reopen, the executive has agreed live music will be permitted for rehearsals and performances with no restriction to background ambient levels of volume.
Audience members must purchase tickets in advance, must have allocated seating and social distancing of 1m (3ft) will be required.